PT - JOURNAL ARTICLE AU - Stamatios Zouras AU - Jeffrey W Stephens AU - David Price TI - Obesity-related hypogonadism: a reversible condition AID - 10.1136/bcr-2017-220416 DP - 2017 Jun 23 TA - BMJ Case Reports PG - bcr-2017-220416 VI - 2017 4099 - http://casereports.bmj.com/content/2017/bcr-2017-220416.short 4100 - http://casereports.bmj.com/content/2017/bcr-2017-220416.full AB - Obesity is associated with hypogonadism. While this association is widely accepted, the underlying mechanisms remain unclear. Furthermore, obesity is a risk factor for hypogonadism and conversely hypogonadism may be a risk factor for obesity. We present the case of a morbidly obese man aged 30 years with hypogonadotrophic hypogonadism that underwent a Roux-en-Y gastric bypass operation. Following the surgical treatment of his obesity, the testosterone level returned to normal with improvements in hypogonadal symptoms, which allowed discontinuation of exogenous testosterone therapy. This case report demonstrates reversal of hypogonadism following weight loss with restoration of gonadal function.