RT Journal Article SR Electronic T1 Sepsis and siderosis, Yersinia enterocolitica and hereditary haemochromatosis JF BMJ Case Reports FD BMJ Publishing Group Ltd SP bcr2016218185 DO 10.1136/bcr-2016-218185 VO 2017 A1 Phoebe A Thwaites A1 Marion L Woods YR 2017 UL http://casereports.bmj.com/content/2017/bcr-2016-218185.abstract AB A 60-year-old woman was admitted with sepsis, relative bradycardia, CT evidence of numerous small liver abscesses and ‘skin bronzing’ consistent with hereditary haemochromatosis (HH). Yersinia enterocolitica O:9 infection was confirmed by serology specimens taken 10 days apart. Iron overload was detected, and homozygous C282Y gene mutation confirmed HH. Liver biopsy revealed grade IV siderosis with micronodular cirrhosis. Haemochromatosis is a common, inherited disorder leading to iron overload that can produce end-organ damage from excess iron deposition. Haemochromatosis diagnosis allowed aggressive medical management with phlebotomy achieving normalisation of iron stores. Screening for complications of cirrhosis was started that included hepatoma surveillance. Iron overload states are known to increase patient susceptibility to infections caused by lower virulence bacteria lacking sophisticated iron metabolism pathways, for example, Yersinia enterocolitica. Although these serious disseminated infections are rare, they may serve as markers for occult iron overload and should prompt haemochromatosis screening.