RT Journal Article SR Electronic T1 Aortic valve replacement for Libman-Sacks endocarditis JF BMJ Case Reports FD BMJ Publishing Group Ltd SP bcr2016215914 DO 10.1136/bcr-2016-215914 VO 2016 A1 Jack B Keenan A1 Rajesh Janardhanan A1 Brandon T Larsen A1 Zain Khalpey YR 2016 UL http://casereports.bmj.com/content/2016/bcr-2016-215914.abstract AB A 24-year-old man with systemic lupus erythematosus and antiphospholipid syndrome complicated by lupus nephritis presented with acute limb ischaemia secondary to an embolus. Following embolectomy, the patient underwent a transthoracic echocardiogram which revealed a large vegetation on all three cusps of the aortic valve. The patient was taken for an urgent aortic valve replacement with a mechanical valve. Cultures of one cusp remained sterile. Histopathological examination of the remaining two cusps revealed sterile fibrin-rich thrombotic vegetations characteristic of non-bacterial thrombotic endocarditis.