TY - JOUR T1 - Aspirin unmasking acquired haemophilia A in a patient with prostate cancer JF - BMJ Case Reports DO - 10.1136/bcr-2016-216890 VL - 2016 SP - bcr2016216890 AU - Julie Omolola Okiro AU - Amjad Zaman Khan AU - Fergus Keane AU - Faiza Murad Y1 - 2016/09/08 UR - http://casereports.bmj.com/content/2016/bcr-2016-216890.abstract N2 - A 72-year-old man, on treatment for prostate cancer, attended the emergency department with his 2nd episode of spontaneous extensive bruising and haematomas. His first presentation was 2 months prior but this was thought to be because of his aspirin and he improved when aspirin was discontinued. On this occasion aspirin had been restarted 7 days before he developed his symptoms. His blood investigation was significant for a much raised activated partial thromboplastin time (aPTT). On his 3rd day of admission he deteriorated clinically with a drastic drop in his haemoglobin and worsening tense haematomas. Blood investigations confirmed the diagnosis of acquired factor VIII deficiency and he subsequently received treatment with factor VIII inhibitor bypassing activity, steroids and immunosuppresants. ER -