PT  - JOURNAL ARTICLE
AU  - Shintaro Dobashi
AU  - Tadashi Fujino
AU  - Takanori Ikeda
TI  - Use of apixaban for an elderly patient with left atrial thrombus
AID  - 10.1136/bcr-2014-203870
DP  - 2014 Jun 24
TA  - BMJ Case Reports
PG  - bcr2014203870
VI  - 2014
4099  - http://casereports.bmj.com/content/2014/bcr-2014-203870.short
4100  - http://casereports.bmj.com/content/2014/bcr-2014-203870.full
AB  - An 86-year-old man had long-standing persistent atrial fibrillation, but had not received any anticoagulants. Transthoracic echocardiography revealed a large thrombus formation in the left atrium. We hesitated to use the conventional anticoagulant, warfarin, because he was very old and had dementia. We decided to resolve the thrombus at our outpatient clinic. He was started on the novel oral anticoagulant, apixaban, 2.5 mg twice daily, which is a direct factor Xa (FXa) inhibitor. After 11 weeks on that therapy, the thrombus formation had almost resolved. During oral anticoagulant therapy, no serious bleeding complications, systemic embolisms or strokes were noted. To the best of our knowledge, we are the first to report that apixaban (5 mg/day) can possibly resolve a thrombus formation in the left atrium.