PT  - JOURNAL ARTICLE
AU  - Sangeeta Panjab Wanjari
AU  - Panjab Vitthalrao Wanjari
AU  - Kalpana A Patidar
AU  - Rajkumar N Parwani
TI  - Papillary cystadenocarcinoma of the hard palate
AID  - 10.1136/bcr-2013-009215
DP  - 2014 Jan 09
TA  - BMJ Case Reports
PG  - bcr2013009215
VI  - 2014
4099  - http://casereports.bmj.com/content/2014/bcr-2013-009215.short
4100  - http://casereports.bmj.com/content/2014/bcr-2013-009215.full
AB  - Papillary cystadenocarcinoma (PCC) is an uncommon malignant tumour of the salivary gland, sometimes involving the minor salivary gland. Previously this entity was classified as an atypical type of adenocarcinoma, malignant papillary cystadenoma, low-grade papillary adenocarcinoma or mucus producing adenopapillary carcinoma. PCC is a glandular tumour with an indolent biological behaviour characterised by cysts and papillary endophytic projections. We report two cases of PCC involving the minor salivary gland of the hard palate. Both the patients presented with a swelling in the palate with difficulty in chewing. MRI revealed an extensively destructive lesion involving hard palate, alveolar ridge and maxillary antrum. Clinical and radiological features suggested the malignant nature of the lesion. Histopathology of incisional biopsy revealed tumour proliferation in a multicystic pattern, with extensive papillary proliferation. Diverse and cellular cytomorphology, and cellular and nuclear pleomorphism with few mitotic figures were the prominent features. Both the lesions were confirmed as PCC.