RT Journal Article SR Electronic T1 Susac's syndrome: an immune mediated endotheliopathy laden with challenges and controversies JF BMJ Case Reports FD BMJ Publishing Group Ltd SP bcr2012008390 DO 10.1136/bcr-2012-008390 VO 2013 A1 Abhishek Malhotra A1 Elizabeth Reyneke A1 Merrilee Needham YR 2013 UL http://casereports.bmj.com/content/2013/bcr-2012-008390.abstract AB Susac's syndrome is a microangiopathy of the retina, inner ear and brain manifesting as a triad of encephalopathy, hearing loss and branch retinal artery occlusion. The pathological mechanism is thought to be an immune-mediated small vessel vasculitis with some pathophysiological similarity to dermatomyositis. Awareness and early recognition of this syndrome is important as early treatment with immunosuppression can minimise cognitive, audiological and visual sequelae. We report a case of a 33-year-old woman who presented with the characteristic syndrome. She was treated with immunomodulatory therapy and remains well 2 years postpresentation with no new events.