TY - JOUR T1 - Susac's syndrome: an immune mediated endotheliopathy laden with challenges and controversies JF - BMJ Case Reports DO - 10.1136/bcr-2012-008390 VL - 2013 SP - bcr2012008390 AU - Abhishek Malhotra AU - Elizabeth Reyneke AU - Merrilee Needham Y1 - 2013/08/19 UR - http://casereports.bmj.com/content/2013/bcr-2012-008390.abstract N2 - Susac's syndrome is a microangiopathy of the retina, inner ear and brain manifesting as a triad of encephalopathy, hearing loss and branch retinal artery occlusion. The pathological mechanism is thought to be an immune-mediated small vessel vasculitis with some pathophysiological similarity to dermatomyositis. Awareness and early recognition of this syndrome is important as early treatment with immunosuppression can minimise cognitive, audiological and visual sequelae. We report a case of a 33-year-old woman who presented with the characteristic syndrome. She was treated with immunomodulatory therapy and remains well 2 years postpresentation with no new events. ER -