PT - JOURNAL ARTICLE AU - Sowjanya Dasari AU - Kushal Naha AU - Manjunath Hande AU - G Vivek TI - A novel subtype of myeloproliferative disorder? JAK2V617F-associated hypereosinophilia with hepatic venous thrombosis AID - 10.1136/bcr-2013-200087 DP - 2013 Aug 30 TA - BMJ Case Reports PG - bcr2013200087 VI - 2013 4099 - http://casereports.bmj.com/content/2013/bcr-2013-200087.short 4100 - http://casereports.bmj.com/content/2013/bcr-2013-200087.full AB - We report the case of a 27-year-old man, presenting with one episode of massive haematemesis and a history of persistent eosinophilia for the past 8 months. An evaluation revealed hepatic cirrhosis with portal hypertension, secondary to chronic Budd-Chiari syndrome. Further investigations confirmed a diagnosis of hypereosinophilic syndrome. Molecular genetic analysis was negative for FIP1L1-PDGFRA gene rearrangement, but positive for JAK2V617F mutation.