TY - JOUR T1 - Haemophagocytic lymphohistiocytosis mimicking septic shock after the initiation of chemotherapy for squamous cell sarcinoma of the neck JF - BMJ Case Reports DO - 10.1136/bcr-2013-009651 VL - 2013 SP - bcr2013009651 AU - Madan Raj Aryal AU - Madan Badal AU - Smith Giri AU - Shambhu Aryal Y1 - 2013/06/25 UR - http://casereports.bmj.com/content/2013/bcr-2013-009651.abstract N2 - Haemophagocytic lymphohistiocytosis (HLH) is a rare but potentially fatal disorder resulting from a highly stimulated immune response with uncontrolled accumulation of lymphocytes and macrophages in multiple organs. Both the inherited and acquired forms of this disease exist; the latter can sometimes occur secondary to different malignancies. In this report, we present a middle-aged Hispanic man who presented with features of septic shock during the course of chemotherapy for squamous cell carcinoma of the neck. Despite aggressive treatment for septic shock, he rapidly deteriorated and died after 30 h of admission. Autopsy findings confirmed a diagnosis of HLH. HLH should be recognised as a serious adverse event during chemotherapy for different malignancies including squamous cell carcinoma of the neck. ER -