PT  - JOURNAL ARTICLE
AU  - Katell Autret
AU  - Annabelle Arnould
AU  - Sarah Mathieu
AU  - Philippe Azouvi
TI  - Transient improvement of poststroke apathy with zolpidem: a single-case, placebo-controlled double-blind study
AID  - 10.1136/bcr-2012-007816
DP  - 2013 Feb 08
TA  - BMJ Case Reports
PG  - bcr2012007816
VI  - 2013
4099  - http://casereports.bmj.com/content/2013/bcr-2012-007816.short
4100  - http://casereports.bmj.com/content/2013/bcr-2012-007816.full
AB  - We report the case of a 44-year-old patient with severe and disabling apathy nearly 2 years after a right hemisphere haemorrhagic stroke. The effect of a single dose of zolpidem was tested over a 2-week period, in alternation with either no treatment or a placebo in a double-blind randomised trial. Zolpidem was associated with a dramatic improvement in apathy, as assessed with the Apathy Inventory and the Behavioral Dysexecutive Syndrome Inventory. No adverse effect occurred during the trial.