TY - JOUR T1 - Small colony variant-producing <em>S aureus</em> prosthesis joint infection highlighted by sonication and treated with prolonged high doses of daptomycin JF - BMJ Case Reports DO - 10.1136/bcr-2013-008637 VL - 2013 SP - bcr2013008637 AU - Camille Piffaut AU - Sébastien Lustig AU - Frédéric Laurent AU - Christian Chidiac AU - Tristan Ferry AU - on behalf of the Lyon BJI Study Group Y1 - 2013/03/25 UR - http://casereports.bmj.com/content/2013/bcr-2013-008637.abstract N2 - An 80-year-old woman with a history of β-lactam allergy was admitted for chronic knee prosthesis joint infection (PJI) (figure 1A). The prosthesis was removed and sonicated as previously described (400 ml of Ringer solution was added in a sterile box containing the explanted prosthesis, vortexing was performed before and after sonication in ultrasound bath, and then 100 μl of sonicate fluid was plated onto aerobic and anaerobic medium and broth).1 All peroperative samples revealed methicillin-susceptible Staphylococcus aureus in cultures, whereas the sonicate fluid culture yielded additional S aureus small colony variant phenotype (SCV) (figure 1B). … ER -