RT Journal Article
SR Electronic
T1 Anaphylaxis to ibuprofen in a 12-year-old boy
JF BMJ Case Reports
FD BMJ Publishing Group Ltd
SP bcr2012007873
DO 10.1136/bcr-2012-007873
VO 2013
A1 Emily Kay
A1 Moshe Ben-Shoshan
YR 2013
UL http://casereports.bmj.com/content/2013/bcr-2012-007873.abstract
AB Non-steroidal anti-inflammatory (NSAIDs) drugs are a group of medications acting through cyclooxygenase  (COX-1) and cyclooxygenase  (COX-2) enzymes inhibition. Hypersensitivity reactions to NSAIDs, although not rare, are poorly characterised and often go undiagnosed especially in children. We present in this paper a case of ibuprofen anaphylaxis that exemplifies the challenges involved in diagnosis and management of hypersensitivity reactions to NSAIDs.