@article {Kaybcr2012007873, author = {Emily Kay and Moshe Ben-Shoshan}, title = {Anaphylaxis to ibuprofen in a 12-year-old boy}, volume = {2013}, elocation-id = {bcr2012007873}, year = {2013}, doi = {10.1136/bcr-2012-007873}, publisher = {BMJ Publishing Group}, abstract = {Non-steroidal anti-inflammatory (NSAIDs) drugs are a group of medications acting through cyclooxygenase ~(COX-1) and cyclooxygenase ~(COX-2) enzymes inhibition. Hypersensitivity reactions to NSAIDs, although not rare, are poorly characterised and often go undiagnosed especially in children. We present in this paper a case of ibuprofen anaphylaxis that exemplifies the challenges involved in diagnosis and management of hypersensitivity reactions to NSAIDs.}, URL = {https://casereports.bmj.com/content/2013/bcr-2012-007873}, eprint = {https://casereports.bmj.com/content/2013/bcr-2012-007873.full.pdf}, journal = {Case Reports} }