RT Journal Article SR Electronic T1 Efficacy and cost of micronutrient treatment of childhood psychosis JF BMJ Case Reports FD BMJ Publishing Group Ltd SP bcr2012007213 DO 10.1136/bcr-2012-007213 VO 2012 A1 Megan Rodway A1 Annette Vance A1 Amany Watters A1 Helen Lee A1 Elske Bos A1 Bonnie J Kaplan YR 2012 UL http://casereports.bmj.com/content/2012/bcr-2012-007213.abstract AB Psychosis is difficult to treat effectively with conventional pharmaceuticals, many of which have adverse long-term health consequences. In contrast, there are promising reports from several research groups of micronutrient treatment (vitamins, minerals, amino acids and essential fatty acids) of mood, anxiety and psychosis symptoms using a complex formula that appears to be safe and tolerable. We review previous studies using this formula to treat mental symptoms, and present an 11-year-old boy with a 3-year history of mental illness whose parents chose to transition him from medication to micronutrients. Symptom severity was monitored in three clusters: anxiety, obsessive compulsive disorder and psychosis. Complete remission of psychosis occurred, and severity of anxiety and obsessional symptoms decreased significantly (p<0.001); the improvements are sustained at 4-year follow-up. A cost comparison revealed that micronutrient treatment was <1% of his inpatient mental healthcare. Additional research on broad-spectrum micronutrient treatment is warranted.