RT Journal Article
SR Electronic
T1 Placentomegaly and placental mesenchymal dysplasia
JF BMJ Case Reports
FD BMJ Publishing Group Ltd
SP bcr2012007777
DO 10.1136/bcr-2012-007777
VO 2012
A1 Minakshi Rohilla
A1 Sujata Siwatch
A1 Vanita Jain
A1 Raje Nijhawan
YR 2012
UL http://casereports.bmj.com/content/2012/bcr-2012-007777.abstract
AB A 23-year-old primigravida presented to the labour ward at 37 weeks gestation referred with intrauterine growth restriction, oligohydramnios and placentomegaly. Differential diagnoses of placentomegaly were considered. Her antenatal blood screening tests were normal. There were no fetal malformations. However, triple screen and fetal karyotype were not done as patient presented late in pregnancy. The patient soon went into spontaneous labour and delivered a girl weighing 2.15 kg with a normal Apgar score. The cord was long and twisted; placenta was bulky, 1.7 kg, with prominent grape-like vesicles involving whole placenta with a rim of normal placenta at the periphery. Microscopy showed some areas of multiple villi with marked hydropic changes and myxoid degeneration, preserved vasculature and no trophoblastic proliferation. Placental mesenchymal dysplasia was thus diagnosed. The baby had no evidence of Beckwith-Wiedemann syndrome. The child is now 3 years old with normal development and is doing well.