RT Journal Article
SR Electronic
T1 A 3-month-old baby with H1N1 and Guillain–Barré syndrome
JF BMJ Case Reports
FD BMJ Publishing Group Ltd
SP bcr1220115462
DO 10.1136/bcr.12.2011.5462
VO 2012
A1 Alexandra Vasconcelos
A1 Francisco Abecasis
A1 Rita Monteiro
A1 Cristina Camilo
A1 Marisa Vieira
A1 Mamede de Carvalho
A1 Manuela Correia
YR 2012
UL http://casereports.bmj.com/content/2012/bcr.12.2011.5462.abstract
AB Majority of children with pandemic influenza A (H1N1)pdm09 experience mild illness with full recovery without treatment. A previously healthy two and a half month-old girl was admitted to our paediatric intensive care unit because of severe respiratory failure with A (H1N1)pdm09 infection. Despite initial clinical improvement all attempts to extubate to non-invasive ventilation were unsuccessful and 2 to 3 weeks after symptom onset she started periods of cardiovascular instability and a progressive neurological deterioration with distal symmetrical progressive motor weakness and areflexia. All investigations were normal except elevated liver enzymes and cerebrospinal fluid examination that revealed elevated protein without pleocytosis. A possible diagnosis of Guillain–Barré syndrome (GBS) was considered and electromyogram was compatible with axonal form of GBS. To our knowledge this is the youngest case of GBS acquired postnatally and the first in children associated with H1N1 virus.