RT Journal Article
SR Electronic
T1 Primary angiosarcoma of the bladder in a young female
JF BMJ Case Reports
FD BMJ Publishing Group Ltd
SP bcr1120103484
DO 10.1136/bcr.11.2010.3484
VO 2011
A1 Richard R Warne
A1 Jeremy S L Ong
A1 Bret Snowball
A1 Justin B Vivian
YR 2011
UL http://casereports.bmj.com/content/2011/bcr.11.2010.3484.abstract
AB Our case report pertains to a 32-year-old woman initially presenting with left flank pain and gross haematuria throughout her urinary stream. CT of her kidney/ureter/bladder (CT KUB) revealed ureteric dilatation to the level of the bladder without evidence of renal calculus and subsequently a stent was inserted. She represented a month later with contralateral flank pain, and a transuretheral resection of bladder tumour was performed. Histopathological diagnosis was epithelioid angiosarcoma. Further imaging (MRI pelvis) revealed that the tumour arose from the posterior bladder wall with local invasion and regional lymph node metastasis. Ifosfamide and epirubicin chemotherapy with single-fraction radiotherapy induced significant reduction in tumour bulk, although this initial response was followed by the development of symptoms suggestive of disease progression. She died 19 months after initial diagnosis with persistent pulmonary and vertebral metastases although no autopsy was performed.