RT Journal Article SR Electronic T1 Incontinentia pigmenti in the neonatal period JF BMJ Case Reports FD BMJ Publishing Group Ltd SP bcr0120113708 DO 10.1136/bcr.01.2011.3708 VO 2011 A1 Vera Rodrigues A1 Filipa Diamantino A1 Olga Voutsen A1 Manuel Sousa Cunha A1 Rosalina Barroso A1 Maria João Paiva Lopes A1 Helena Carreiro YR 2011 UL http://casereports.bmj.com/content/2011/bcr.01.2011.3708.abstract AB Incontinentia pigmenti (IP) is a rare multisystem disease, X linked dominant disorder. As all X linked dominant diseases, it is usually male-lethal. Female newborn admitted to the neonatal intensive care unit on the first day of life was diagnosed as having probable herpetic infection with vesicular skin lesions distributed on upper right limb and inferior limbs. Family history showed that her 22-year-old mother had hypopigmented lesions on the lower limbs and her 13-month-old sister had hyperpigmented lesions on the trunk and limbs. In newborns, herpes infection emerges as the principal diagnosis of vesicular rash, due to the importance of precocious diagnosis and treatment. Other hypothesis must be considered in a newborn with vesicobullous rash, such as IP.