RT Journal Article
SR Electronic
T1 Focal nodular hyperplasia with major sinusoidal dilatation: a misleading entity
JF BMJ Case Reports
FD BMJ Publishing Group Ltd
SP bcr0920103311
DO 10.1136/bcr.09.2010.3311
VO 2010
A1 Hervé Laumonier
A1 Nora Frulio
A1 Christophe Laurent
A1 Charles Balabaud
A1 Jessica Zucman-Rossi
A1 Paulette Bioulac-Sage
YR 2010
UL http://casereports.bmj.com/content/2010/bcr.09.2010.3311.abstract
AB Focal nodular hyperplasia (FNH) is a benign liver lesion thought to be a non-specific response to locally increased blood flow. Although the diagnosis of FNH and hepatocellular adenoma (HCA) has made great progress over the last few years using modern imaging techniques, there are still in daily practice some difficulties concerning some atypical nodules. Here, the authors report the case of a 47-year-old woman with a single liver lesion thought to be, by imaging, an inflammatory HCA with major sinusoidal congestion. This nodule was revealed to be, at the microscopical level and after specific immunostaining and molecular analysis, an FNH with sinusoidal dilatation (so-called telangiectatic focal nodular hyperplasia).