PT  - JOURNAL ARTICLE
AU  - P Börcek
AU  - S L Asa
AU  - F Gentili
AU  - S Ezzat
AU  - T-R Kiehl
TI  - Brain metastasis from medullary thyroid carcinoma
AID  - 10.1136/bcr.09.2010.3301
DP  - 2010 Jan 01
TA  - BMJ Case Reports
PG  - bcr0920103301
VI  - 2010
4099  - http://casereports.bmj.com/content/2010/bcr.09.2010.3301.short
4100  - http://casereports.bmj.com/content/2010/bcr.09.2010.3301.full
AB  - The brain is an exceedingly rare site of metastasis in medullary thyroid carcinoma (MTC). A 50-year-old female who had a history of micro-MTC 11 years prior developed a cerebellar metastasis which was incidentally discovered. Imaging revealed a right cerebellar hemispheric mass with contrast enhancement on CT scans. Histopathologic exam demonstrated a metastatic tumour composed of nodules and sheets of large tumour cells with abundant cytoplasm. Immunohistochemistry confirmed the origin from a MTC. This case report highlights the unique features of an unusual metastatic brain tumour, which followed an indolent course for a long time despite multiple distant metastases.