PT  - JOURNAL ARTICLE
AU  - Vinodh Nanjanna Devakumar
AU  - Madhura Castelino
AU  - Shien-Ching Chow
AU  - Lee-Suan Teh
TI  - Wegener’s granulomatosis in pregnancy: a case report and review of the medical literature
AID  - 10.1136/bcr.09.2009.2296
DP  - 2010 Jan 01
TA  - BMJ Case Reports
PG  - bcr0920092296
VI  - 2010
4099  - http://casereports.bmj.com/content/2010/bcr.09.2009.2296.short
4100  - http://casereports.bmj.com/content/2010/bcr.09.2009.2296.full
AB  - A Caucasian woman in the third trimester of her sixth pregnancy was diagnosed with Wegener’s granulomatosis (WG) following investigation for recurrent ear infections and a persistent dry cough. Chest radiograph showed granulomatous lesions and the c-ANCA (antineutrophil cytoplasmic antibody) was strongly positive. She required pulsed methylprednisolone and cyclophosphamide followed by oral prednisolone and azathioprine to control the disease process during and after pregnancy. Neither the disease nor aggressive treatment adversely affected the pregnancy and she delivered a healthy baby girl by elective induction at 37 weeks. A review of the literature on Wegener’s granulomatosis in pregnancy is presented.