TY - JOUR T1 - Aggressive Dupuytren's diathesis in a young woman JF - BMJ Case Reports DO - 10.1136/bcr.12.2009.2592 VL - 2010 SP - bcr1220092592 AU - Ivan Couto-Gonzalez AU - Beatriz Brea-Garcia AU - Antonio Taboada-Suárez AU - Eduardo González-Álvarez Y1 - 2010/01/01 UR - http://casereports.bmj.com/content/2010/bcr.12.2009.2592.abstract N2 - Dupuytren's disease is a palmar fascia pathology characterised by flexion contracture of the involved fingers in late stages. It has been described a higher prevalence in northern populations, especially in men in the fifth or sixth decade of life.1 Alcohol consumption, liver disease, diabetes mellitus, epilepsy and some of its treatments, tobacco smokers or hand workers are only a example of the different aetiologies proposed. There are a group of patients presenting with more aggressive clinical manifestation named Dupuytren's diathesis. This subtype could frequently present a positive family history, ectopic fibromatosis and bilateral hand affectation. The authors present a 24-year-old woman referred to the Plastic Surgery Department because severe fingers contracture with an associated aggressive plantar fibromatosis. She referred familial history in her first degree relatives (mother and three of seven brothers and sisters). The first clinical manifestations in her hand began when she was 7 years old. ER -