RT Journal Article
SR Electronic
T1 Practice of symptomatic treatment in the era of evidence-based medicine: report of 2 cases of diagnosis of Sheehan’s syndrome delayed till eighth decade
JF BMJ Case Reports
FD BMJ Publishing Group Ltd
SP bcr0920092276
DO 10.1136/bcr.09.2009.2276
VO 2010
A1 Abdul Majid Wani
A1 Waleed Mohd Hussain
A1 Mousa Ali Al Mejally
A1 Abdulhakeem Amroon Banjar
A1 Khaled Shawkat Ali
A1 Amer Mohd Khoujah
A1 Sadeya Hanif Raja
A1 Mazen G Bafaraj
A1 Wail Al Miamini
A1 Mubeena Akhtar
YR 2010
UL http://casereports.bmj.com/content/2010/bcr.09.2009.2276.abstract
AB Sheehan’s syndrome, first described in 1937, is characterised by postpartum haemorrhage, pituitary necrosis, lactational failure and hypopitutarism. Presentation is variable and late presentations are not unusual due to partial ischaemic injury of the pituitary and gradual loss of endocrine function. A history of postpartum haemorrhage is usual but in some cases it is not elicited. Presentations such as malaise, fatigue, hypoglycaemia, decline in cognition, hyponatraemia, pancytopoenia, osteoporosis, secondary infertility, confusion and coma have all been reported. Two interesting cases of Sheehan’s syndrome are presented that were diagnosed in the eighth decade; one due to atypical presentation of recurrent hyponatraemia and confusion, another from hypoglycaemic coma and symptoms of malaise and lethargy.