TY - JOUR T1 - Nocardiosis in a patient with rheumatoid athritis treated with rituximab and a summary of reported cases JF - BMJ Case Reports DO - 10.1136/bcr.11.2009.2421 VL - 2010 SP - bcr1120092421 AU - C S Ngiu AU - M S Mohamed Said AU - P Periyasamy AU - S F Low Y1 - 2010/01/01 UR - http://casereports.bmj.com/content/2010/bcr.11.2009.2421.abstract N2 - Rituximab is a B-cell-depleting monoclonal anti-CD20 antibody. It is widely used in haematology and rheumatology. However, usage of rituximab in immunosupressed patient has been associated with various opportunistic infections. The authors reported a case of refractory rheumatoid arthritis treated with rituximab, which later presented with non-resolving pneumonia with pulmonary nodule. Percutaneous computer tomogram guided lung biopsy was arranged to confirm the suspicion of tuberculosis, but did not yield conclusive results. Later, she presented left-chest abscess and underwent incision and drainage. The pus culture and sensitivity confirmed pulmonary nocardiosis with chest wall dissemination. She was treated with 2-week course of trimethoprim sulfamethoxazole and responded. The authors also reviewed published cases of nocardiosis post-rituximab. ER -