TY - JOUR T1 - Radiological findings in cyclical administration of intravenous pamidronate in children with osteoporosis JF - BMJ Case Reports DO - 10.1136/bcr.2007.129692 VL - 2009 SP - bcr2007129692 AU - C Onwuneme AU - K Abdalla AU - N Cassidy AU - O Hensey AU - S Ryan Y1 - 2009/01/01 UR - http://casereports.bmj.com/content/2009/bcr.2007.129692.abstract N2 - A 5-year-old boy with moderately severe osteogenesis imperfecta and spontaneous fractures was treated with serial courses of intravenous pamidronate. Pamidronate is a second-generation bisphosphonate drug that binds strongly to bone mineral and interferes with bone remodelling by slowing osteoclastic bone resorption. It is used in a cyclic dosage of 1 mg/kg/day intravenously on 3 successive … ER -