PT - JOURNAL ARTICLE AU - Anil Bhansali AU - P Jayaprakash AU - Pinaki Dutta AU - Rama Walia AU - P Ravikumar TI - Precocious puberty and a sellar mass AID - 10.1136/bcr.03.2009.1677 DP - 2009 Jan 01 TA - BMJ Case Reports PG - bcr0320091677 VI - 2009 4099 - http://casereports.bmj.com/content/2009/bcr.03.2009.1677.short 4100 - http://casereports.bmj.com/content/2009/bcr.03.2009.1677.full AB - Precocious puberty in a child less than 3 years of age is usually gonadotropin dependent and is often associated with extrasellar central nervous system disorders. The present report describes the case of a 2½-year-old girl who presented with gonadotropin-independent precocious puberty and had a sellar mass. She was referred for neurosurgical intervention to our institute. On investigation, she was found to have primary hypothyroidism of autoimmune aetiology, which is rarely associated with precocious puberty and sellar mass due to thyrotroph hyperplasia. She was successfully treated with levothyroxine, and with this secondary sexual characteristics progressively regressed and the sellar mass disappeared.