TY - JOUR T1 - Dramatic response to levetiracetam in post-ischaemic Holmes’ tremor JF - BMJ Case Reports DO - 10.1136/bcr.08.2008.0643 VL - 2009 SP - bcr0820080643 AU - P Striano AU - Andrea Elefante AU - Antonietta Coppola AU - Fabio Tortora AU - Federico Zara AU - Carlo Minetti Y1 - 2009/01/01 UR - http://casereports.bmj.com/content/2009/bcr.08.2008.0643.abstract N2 - Holmes’ tremor refers to an unusual combination of rest, postural and kinetic tremor of extremities. Common causes of Holmes’ tremor include stroke, trauma, vascular malformations and multiple sclerosis, with lesions involving the thalamus, brain stem or cerebellum. Although some drugs (eg, levodopa and dopaminergic drugs, clonazepam and propranolol) have been occasionally reported to give some benefit, medical treatment of Holmes’ tremor is unsatisfactory, and many patients require thalamic surgery to achieve satisfactory control. We report a patient in whom post-ischaemic Holmes’ tremor dramatically responded to levetiracetam treatment. ER -