PT - JOURNAL ARTICLE AU - Pierre Bourgeois AU - Stéphane Moniotte TI - Lymphatic system anomalies in Crouzon syndrome AID - 10.1136/bcr.07.2008.0586 DP - 2009 Jan 01 TA - BMJ Case Reports PG - bcr0720080586 VI - 2009 4099 - http://casereports.bmj.com/content/2009/bcr.07.2008.0586.short 4100 - http://casereports.bmj.com/content/2009/bcr.07.2008.0586.full AB - Crouzon syndrome is a rare genetic disorder characterised mainly by distinctive malformations of the skull and facial region and caused by mutations in the fibroblast growth factor receptor 2 (FGFR2) gene. No study reported on oedemas related to lymphatic system abnormalities in these patients. A case of Crouzon syndrome displaying classic facial anomalies but also with bilateral lower limb oedema is reported in whom lymphoscintigraphic investigation of the limbs clearly delineated the presence of lymphatic system anomalies.