129 e-Letters

published between 2016 and 2019

  • Vitamin D
    Anne Thomas

    I think it is irresponsible of this author not to mention that there has indeed been research linking vitamin D to Autism and it is quite reasonable for parents to consider that supplements might improve their child's symptoms. https://www.vitamindcouncil.org/health-conditions/autism/ I have certainly seen in clinical practice a reduction in autistic symptoms in patients over the summer months.

    There is also evi...

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  • Anisakidosis as an emerging problem
    Roberto Calisti

    A relevant warning, particularly in front of an Anisakis' wide diffusion outside its traditional environment as a consequence of global warming.

    Nowadays, Anisakis is frequently present in anchovies, sardines and mackerels in Northern Mediterranean too, causing infestations after consuming uncooked or half-cooked fish.

    It is very difficult to recognize Anisakidosis if the suspect doesn't arise and th...

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  • Mouthpiece intermittent positive pressure ventilation: An old yet underutilized technique for long-term management of respiratory muscle failure.
    Royce X. Shou

    Dear Authors,

    We applaud your recognition that daytime mouthpiece intermittent positive pressure ventilation (IPPV) can serve as a practical alternative in cases of end stage respiratory muscle failure in which tracheostomy is usually the eventual conventional intervention of choice among the majority of today's clinicians. Lack of familiarity indeed seems to be the reason open-circuit mouthpiece ventilation, am...

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  • Trousseau's sign at the emergency department
    Arvind Ganesh Kulkarni

    The Trousseau's sign as described here is usually indicative of Hypocalcemia as was evident in this patient. However its sensitivity as well as specificity may not be that high as referred in the case report. It can be induced by hyperventilation leading to respiratory alkalosis even in so called normal healthy persons. This patient did have hypocalcemia as well as hypomagnesemia and hypokalemia in addition all probab...

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  • Case of CML lymphoid blast crisis presenting as bilateral breast masses
    Arvind Ganesh Kulkarni

    This is an interesting case. However the postulation proposed by the authors that a case of CML going into blast crisis of Lymphoid variety appears to be slightly far from reality. Knowing that haemopoetic stem cells can develop in any cell variety it is possible that the cells described could morphologically resemble Lymphoblasts but are in fact better labeled as Undifferentiated Blasts. The patient had many symptoms of...

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  • Haemophilia A related haematoma. management in resourse constrained settings
    Arvind Ganesh Kulkarni

    Haemophilia A is not so uncommon in India but perhaps remains unnoticed or non cared for because of the non availability of the replacement therapy or the cost factors for the therapy. This patient appears to have a milder form of the condition as no mention has been made about the frequency with which he requires the replacement of factor VIII, although it has been mentioned that at some stage the levels were less than...

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  • Successful treatment of recurrent rectal prolapse using three Thiersch sutures in children
    Jean-Luc Faucheron

    We read with interest the article from Chauhan Kashif et al, entitled "Successful treatment of recurrent rectal prolapse using 3 Thiersch sutures in an 8-year-old boy" [1] and would like to add some comments. The authors proposed a novel technique of Thiersch procedure using three sutures that included one non absorbable polypropylene suture to successfully treat a re-recurrent full-thickness rectal prolapse in an 8- year-old...

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  • Opportunity for a "one health" approach overlooked?
    Anne Fawcett

    To Whom It May Concern

    "Lick of death: Capnocytophaga canimorsus is an important cause of sepsis in the elderly"1 describes an excellent outcome thanks to an elegant diagnostic work up and excellent treatment. However, I believe the headline "Lick of death" is unnecessarily fear-mongering and unwarranted (the patient, after all, did not die). Additionally, while the authors should be congratulated for educating...

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  • 7q11.23-q21.2 microdeletion: 2 years follow-up
    George T. Vasileiadis

    As reported in the original article, the developmental assessment at 13.5 months (adjusted for prematurity) showed a global developmental delay.

    Bayley III assessment at 24.8 months (adjusted for prematurity) confirmed the global developmental delay affecting cognitive, communication and motor domains (percentile ranks: 0.4, 4, 0.4, respectively). The passive tone of his upper extremities was symmetrical bilat...

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  • Gastrointestinal bleeding secondary to trimethoprim-sulfamethoxol induced vitamin K deficiency
    Arvind Ganesh Kulkarni

    The combination of trimethoprim and sulafamethoxole has been used for the prophylaxis of malaria for over several decades. While the development of vitamin K deficiency due to this drug combination is theoretically possible, it is not very common. There are many risk factors for vitamin K deficiency, such as diet, interactions with other drugs and basic liver function. To state that this drug combination caused vitamin K...

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