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A Rare case of recurrent Guillain-Barré syndrome without albuminocytological dissociation
  1. Anudeep Yelam1,
  2. Elanagan Nagarajan2,
  3. Raghav Govindarajan1,
  4. Pradeep C Bollu1
  1. 1 Department of Neurology, University of Missouri Health Care, Columbia, Missouri, USA
  2. 2 Department of Neurology, Howard Hughes Medical Institute—University of Missouri Columbia School of Medicine, Columbia, Missouri, USA
  1. Correspondence to Dr Elanagan Nagarajan, nagarajane{at}


Guillain-Barré syndrome (GBS) is an immune-mediated polyneuropathy, often preceded by an illness. It is a self-limiting illness in most of the cases, but recurrence is rare and can be seen in about 1%–6% of patients. GBS is characterised by progressive, symmetrical, proximal and distal weakness. Areflexia and sensory disturbances are also common. Patients with GBS usually have albuminocytological dissociation on cerebrospinal fluid (CSF) analysis. This is a case of a 69-year-old woman with recurrent GBS and normal CSF findings.

  • neurology (drugs and medicines)
  • general practice / family medicine
  • immunology
  • peripheral nerve disease

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  • Contributors AY was responsible for study design, study concept, data collection, drafting and revision of the manuscript with support from EN, PCB and RG. RG and PCB conceived the original idea for this case report. All the people mentioned have contributed to the final version of this manuscript. All the people mentioned have been involved in the patient care.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.