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Clear cell chondrosarcoma of the larynx
  1. Thomas Hendriks1,
  2. Felipe Cardemil2,
  3. Chady Sader1,2
  1. 1Fiona Stanley Hospital, Murdoch, Western Australia, Australia
  2. 2Sir Charles Gairdner Hospital, Perth, Western Australia, Australia
  1. Correspondence to Dr Thomas Hendriks, thomas.hendriks{at}


Chondrosarcomas represent a group of malignant tumours composed of cells producing cartilage, and clear cell chondrosarcomas (CCC) represent a variant of these. A rare case of a laryngeal CCC is presented. The patient was a 70-year-old man who presented with a 6-week history of throat pain, worsening dysphonia and a lump in the neck. Examination revealed a level 3 neck mass and positron emission tomography imaging revealed a metabolically active right laryngeal mass. Biopsies revealed a cartilaginous neoplasm. The patient underwent total laryngectomy, and the pathology confirmed CCC of the larynx. Chondrosarcomas are the most common type of sarcoma in the larynx but the CCC variant is rare. CCC are usually low-grade tumours affecting long bones, with a male predominance. Less than six cases have been described in the literature affecting the larynx. Management of these malignancies is complete surgical excision given the high risk of local recurrence.

  • ear, nose and throat/otolaryngology
  • head and neck cancer
  • otolaryngology / ent
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  • Contributors TH prepared the initial manuscript, and this was edited by FC and CS. All authors approved of submission of the final manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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