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Summary
The cornerstone modality of treatment of central mucoepidermoid carcinoma (CMEC) of the mandible is surgery, optimally, an en bloc resection with/without segmental or hemimandibulectomy. Notwithstanding the documentation of a survival benefit in few case reports with the addition of postoperative radiotherapy in carefully selected high-risk patients, there does not exist a clearly defined consensus regarding the role of adjuvant radiotherapy. We report the case of a 49-year-old man who presented with right lower jaw swelling which on imaging was found to be a multiloculated lesion causing bony expansion and cortical destruction of the mandible and was diagnosed with CMEC after radiological and histopathological criteria were met. He underwent right hemimandibulectomy and histopathology showed squamous and mucinous cells with positive mucicarmine staining and characteristic immunohistochemistry markers confirming the diagnosis of CMEC. He subsequently underwent adjuvant radiotherapy and is disease free 5 years since treatment completion.
- head and neck cancer
- radiotherapy
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Footnotes
Contributors The case report was conceptualised and the manuscript reviewed by SN. MS drafted the manuscript. Surgical management of this case was done by RM, and she also contributed to revision of the surgical aspects of the case report. Histopathological and immunohistochemistry reporting along with review of relevant literature was done by TC. The patient received radiotherapy under the care of SN.
Funding This research received no specific grant from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests SN is consultant, Medical Affairs in Varian Medical Systems, India. All other authors have no conflicts of interests to declare.
Patient consent Obtained.
Provenance and peer review Not commissioned; externally peer reviewed.