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Primary amenorrhoea and clitoromegaly in a nulliparous woman: successful medical and surgical management
  1. Aruna Nigam,
  2. Arifa Anwar Elahi,
  3. Neha Varun,
  4. Nidhi Gupta
  1. Department of Obstetrics and Gynaecology, Hamdard Institute of Medical Sciences and Research, New Delhi, India
  1. Correspondence to Dr Aruna Nigam, prakasharuna{at}


Clitoromegaly is an important sign of virilisation and poses difficulty in sex determination, when present since birth. The diagnosis and treatment in an adult is a major challenge to the treating gynaecologist. The primary reason for its development is androgen excess due to congenital adrenal hyperplasia, polycystic ovarian syndrome, ovarian virilising tumours, neurofibromas, adrenal neoplasm and prolonged intake of anabolic steroids. A case of young nulliparous married woman who presented with primary amenorrhoea and clitoromegaly and was managed successfully has been reported.

  • endocrine system
  • obstetrics, gynaecology and fertility
  • adrenal disorders

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  • Contributors AN wrote the manuscript. AN, AAE and NV helped in the management of the case. NG helped in writing the case.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.