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CASE REPORT
Splenic granulomas: a rare manifestation of Mycobacterium avium complex in an immunocompetent host
  1. Nupoor Acharya1,
  2. Arghya Chattopadhyay1,
  3. Kusum Sharma2,
  4. Aman Sharma1
  1. 1Department of Internal Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India
  2. 2Medical Microbiology, Post Graduate Institute of Medical Education and Research, Chandigarh, India
  1. Correspondence to Professor Aman Sharma, amansharma74{at}yahoo.com

Summary

Infections caused by Mycobacteriumavium complex (MAC) are commonly seen in immunocompromised individuals. Though disseminated MAC infections with splenic granulomas are seen in some patients, MAC infection clinically manifesting as only splenic granulomas is rare. This presentation is even less common in immunocompetent individuals. We report a case of a young adult who presented with fever of unknown origin and was found to have multiple splenic granulomas. Fine needle aspiration cytology and PCR for Mycobacterium tuberculosis of the granulomas revealed a diagnosis of MAC infection. The patient was not found to have any immunodeficiency on investigations. This case is perhaps the first case of MAC clinically presenting as splenic granulomas in an immunocompetent individual.

  • TB and other respiratory infections
  • infectious diseases
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Footnotes

  • Contributors NA: involved in diagnosis and management of the case and prepared the manuscript. AC: involved in diagnosis and management of the case and prepared the manuscript. AS: involved in diagnosis and management of the case and reviewed the manuscript. KS: performed the multiplex PCR and reviewed the manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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