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Cutaneous nocardiosis by a new pathogenic species: Nocardia grenadensis
  1. Rui Pedro Santos1,
  2. Juliana Almeida2,
  3. Filipa Tavares Almeida3,
  4. Maria da Luz Duarte4
  1. 1Department of Dermatology, Hospital de Braga, Braga, Portugal
  2. 2Department of Clinical Pathology, Hospital de Braga, Braga, Portugal
  3. 3Dermatovenereology, Hospital de Braga, Braga, Portugal
  4. 4Dermatology, Hospital de Braga, Braga, Portugal
  1. Correspondence to Dr Rui Pedro Santos, drruisantos{at}, drruisantos{at}


Nocardiosis is a rare, predominantly opportunistic, suppurative disease caused by bacteria of the order Actinomycetales. There are currently more than 100 species of Nocardia described, less than half are pathogenic to humans. Cutaneous nocardiosis can be caused by direct inoculation from a contaminated material or by secondary dissemination. The authors present a 70-year-old man with an autoimmune haemolytic anaemia treated with prednisolone and azathioprine. The patient presented multiple erythematous tender nodules with linear distribution and proximal progression along the left upper limb with 2 months of evolution. The skin biopsy revealed non-specific inflammation with areas of abscess. Culture was positive for bacteria of the genus Nocardia, and molecular techniques revealed Nocardia grenadensis. The patient was treated with minocycline with good response, but the disease recurred. N. grenadensis was first identified in 2012 in a bioprospecting process. The authors now describe the first case of cutaneous nocardiosis caused by N. grenadensis.

  • dermatology
  • medical education
  • medical management
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  • Contributors RPS and JA contributed to planning, conduct and reporting of the work. RPS, FTA and MdLD contributed to the conception and design of the work. All the authors are responsible for the overall content.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent Next of kin consent obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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