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Neurogenic pulmonary oedema complicating a lateral medullary infarct
  1. Hussain M Raja1,2,
  2. Amit V Herwadkar1,
  3. Kyri Paroutoglou1,
  4. James B Lilleker1
  1. 1The Greater Manchester Neuroscience Centre, Manchester Academic Health Science Centre, Salford Royal NHS Foundation Trust, Salford, M6 8HD, UK
  2. 2The University of Manchester, UK
  1. Correspondence to Dr James B Lilleker, james.lilleker{at}


Neurogenic pulmonary oedema (NPO) is a rare clinical syndrome of pulmonary oedema occurring secondary to an insult of the central nervous system (CNS). The exact aetiology of this disorder is unknown. NPO can be fatal and poor awareness and identification of this entity, particularly in terms of misdiagnosis as primary pulmonary or cardiac disease, can result in suboptimal management and outcomes. We describe the presentation and management of a 68-year-old woman with an acute left lateral medullary stroke complicated by pulmonary oedema. The likely aetiology is discussed, and important learning points are highlighted.

  • neurology
  • brain stem / cerebellum
  • neuroimaging
  • stroke
  • heart failure

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  • Contributors HMR: drafted and updated the manuscript in response to author and patient comments. AVH: reviewed neuroradiology and provided images for publication, critically reviewed manuscript. KP: reviewed patient (consultant in charge), critically reviewed manuscript. JBL: Reviewed patient (on-call registrar), had the original idea and oversaw the project and critically reviewed and finalised the manuscript. All authors have reviewed the final version of the manuscript and agree with its contents.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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