Article Text

Download PDFPDF
Case of colonic mucosal Schwann cell hamartoma and review of literature on unusual colonic polyps
  1. JayaKrishna Chintanaboina,
  2. Kofi Clarke
  1. Penn State Milton S Hershey Medical Center, Hershey, Pennsylvania, USA
  1. Correspondence to Dr JayaKrishna Chintanaboina, jk_chintanaboina{at}


Mucosal Schwann cell hamartomas (MSCH) are benign mesenchymal tumours rarely seen in the gastrointestinal tract. They occasionally present as incidental sessile polyps during colonoscopy. A 55-year-old asymptomatic female patient with a medical history of multiple sclerosis presented for a screening colonoscopy. A 5 mm low-risk tubular adenoma was noted in the caecum, and a second 5 mm polyp was found in the ascending colon. Histopathology of the ascending colon polyp showed proliferation of spindle cells without ganglion cells in the lamina propria. Immunohistochemical findings are compatible with an MSCH. Surveillance colonoscopy was scheduled in 5 years based on the presence of a single low-risk tubular adenoma.

  • endoscopy
  • colon cancer

Statistics from


  • Contributors JC: wrote the manuscript. KC: reviewed, edited and finalised the manuscript. Also performed the colonoscopy.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.