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Acute presentation of a partially obstructing laryngeal tumour: adjuvant agents to gaseous induction of anaesthesia
  1. Natalie Constable1,
  2. Carolyn Thomas2,
  3. Martyn Jones3,
  4. Matt Walters4
  1. 1Anaesthetics, University Hospitals Bristol NHS Foundation Trust, Bristol, UK
  2. 2Anaesthetics, Sherwood Forest Hospitals NHS Foundation Trust, Sutton-In-Ashfield, UK
  3. 3Anaesthetics, Nottingham University Hospitals NHS Trust, Nottingham, UK
  4. 4Anaesthetics, Royal Derby Hospital, Derby, UK
  1. Correspondence to Dr Natalie Constable, natalie.constable{at}


We present the case of a 53-year-old man who attended our emergency department with stridor. He had recently undergone investigation for possible glottic cancer. We discuss the airway management of such a case. We believe this to be the first description of propofol target controlled infusion and clonidine to supplement a sevoflurane gas induction, in order to obtund response to intubation while maintaining spontaneous ventilation. We also consider how airway interventions may impact prognosis and need to be considered.

  • anaesthesia
  • cancer intervention
  • ear, nose and throat/otolaryngology

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  • Contributors NC is the lead author and contributed to the literature review, write up of case and preparation of figures. CT contributed significantly to all sections. MJ contributed significantly to discussion and conclusions. MW is the senior author and contributed to discussion.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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