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A misplaced peripherally inserted central catheter presenting as contralateral pleural effusion
  1. Jogender Kumar,
  2. Sudeep K C,
  3. Kanya Mukhopadhyay,
  4. Somosri Ray
  1. Department of Pediatrics, Post Graduate Institute of Medical Education and Research, Chandigarh, India
  1. Correspondence to Professor Kanya Mukhopadhyay, kanyapgi{at}


A preterm neonate born at 27 weeks, with a birth weight of 555 g, was on continuous positive airway pressure (CPAP) for apnoea of prematurity and initially received total parenteral nutrition (TPN) through the umbilical venous catheter. Peripherally inserted central catheter (PICC) was inserted in the left basilica vein on day 8 to continue TPN. The baby developed respiratory distress with persistent hypoxia after TPN was initiated through the PICC line. The baby required mechanical ventilation due to worsening of respiratory distress, and chest X-ray, as well as ultrasound conducted 12 hours, postinfusion of TPN revealed right-sided pleural effusion. On careful observation, we could trace the PICC in the right lung area. The PICC line was removed immediately and the baby improved over the next 18 hours and was extubated to CPAP within the next 48 hours. We report this case of contralateral pleural effusion secondary to malposition of PICC line in an extremely preterm neonate.

  • nutrition
  • neonatal intensive care
  • parenteral / enteral feeding
  • neonatal and paediatric intensive care

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  • Contributors JK, SR and SKC managed the case. JK drafted the manuscript and did the literature search. SR and SKC provided critical inputs in the draft of the manuscript and finalised it. KM provided critical input in diagnosis, management of the case, critically reviewed the manuscript and finalised it. All the authors finally approved the manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent Parental/guardian consent obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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