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Isolated thyroid metastasis from benign phyllodes tumour
  1. Mark R Kho1,2,
  2. Agustina D Abelardo3,4
  1. 1Department of Surgery, University of the Philippines Manila, Manila, Philippines
  2. 2Department of Surgery, Manila Doctors Hospital, Manila, Philippines
  3. 3Department of Pathology, University of the Philippines Manila, Manila, Philippines
  4. 4Department of Pathology, Manila Doctors Hospital, Manila, Philippines
  1. Correspondence to Dr Mark R Kho, mkhomd{at}


We present a rare and interesting case of a 35-year-old woman who initially underwent an uneventful wide excision for a 13 cm left benign phyllodes tumour. She then noted a slowly growing left thyroid nodule 8 months postsurgery which on thyroidectomy 4 years later was shown to be a 6.9cm isolated thyroid metastasis from the phyllodes tumour. As this may be the first reported such case in the literature, implications on histological classification, predictive factors for disease progression, mechanisms of metastasis, and evaluation, management and surveillance of benign phyllodes tumours and thyroid nodule/s with a history of phyllodes tumour can thus be significantly impacted.

  • breast surgery
  • oncology
  • breast cancer

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  • Contributors MRK: designed, conceptualised, gathered all data, drafted and wrote the case report; did the review of literature and is the corresponding author and guarantor. ADA: is responsible for the interpretation and reporting of all the pathological examinations done; reviewed all the specimen slides, carefully selected and obtained images then composed appropriate figure captions; vital participation in the overall planning, analysing, writing and critical revisions of the manuscript was imperative during periodic discussions held throughout the preparation of this manuscript. Both authors approved the final version for consideration for publication and agreed to be accountable for all aspects of the work.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent Next of kin consent obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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