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Mesenteric artery syndrome associated with HAART onset in a patient with HIV
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  1. Jorge Humberto Rodríguez-Quintero,
  2. Oscar Santes,
  3. Jesus Morales-Maza
  1. General Surgery, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico
  1. Correspondence to Dr Jorge Humberto Rodríguez-Quintero, huroqu90{at}gmail.com

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Description

A 28-year-old man (body mass index (BMI) of 15.6 kg/m2) with untreated HIV infection since 2004 was admitted to the hospital with a 3-month headache, generalised weakness and neurocognitive deficit. He underwent head MRI and a ring-enhancing lesion was found in subcortical temporal-occipital location. Cerebral biopsy revealed primary central nervous system lymphoma. The patient received chemotherapy with cytarabine, rituximab and high-dose methotrexate without complications. Simultaneously, he was started on antiretroviral therapy (ritonavir, darunavir, raltegravir and tenofovir). Two weeks after highly active antiretroviral therapy (HAART) onset, he developed sudden abdominal pain, distention and profuse biliary vomit. CT angiography revealed severe dilation of the stomach and duodenum until its third portion with a transition zone at the level of the superior mesenteric artery (SMA) (figure 1).

Figure 1

(A) Axial CT images show compression of the third portion of the duodenum between aorta (blue) and superior mesenteric artery (SMA) (red). Also, dilation of the stomach and proximal duodenum with a collapsed superior mesenteric vein (SMV) (orange) and vena cava (yellow). (B) CT scan taken 20 days before showing the same structures on their original distribution.

An aortomesenteric angle of …

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