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Cerebral venous sinus thrombosis precipitated by Graves’ disease
  1. Abdul Rehman1,2,
  2. Muhammad Ghazanfar Husnain2,
  3. Kamran Mushtaq2,
  4. Mohsen Saleh Eledrisi2
  1. 1 Department of Biological and Biomedical Sciences, Aga Khan University, Karachi, Sindh, Pakistan
  2. 2 Department of Medicine, Hamad Medical Corporation, Doha, Qatar
  1. Correspondence to Dr Abdul Rehman, jsmawais{at}


Cerebral venous sinus thrombosis usually occurs in patients with a precipitating condition such as thrombophilic disorders, pregnancy or due to medications, such as oestrogens. Some case reports have reported the co-occurrence of cerebral venous sinus thrombosis in patients with hyperthyroidism. However, the association of cerebral venous sinus thrombosis with hyperthyroidism remains contentious. We present the case of a patient who presented with a clinical picture of cerebral venous sinus thrombosis with no obvious precipitating factor. Further investigations revealed the presence of hyperthyroidism due to Graves’ disease, which was thought to be the provocative disorder for cerebral venous sinus thrombosis. We would like to draw the attention of clinicians to a possible causative association between cerebral venous sinus thrombosis and hyperthyroidism.

  • thyroid disease
  • stroke

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  • Contributors All authors were involved in direct care of the patient and conceived the idea of writing a case report. AR and MGH collected the data and interpreted it, and wrote down the case presentation section of the manuscript. KM performed a literature review and wrote down the discussion section of the manuscript. MSE substantially reviewed the whole manuscript for important intellectual content. All authors read the manuscript and approved it for submission in its current form.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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