Article Text

Download PDFPDF
‘Pseudo-calcifications’: detection of perfluorocarbon residue on a computed tomography scan 15 years after liquid ventilation therapy at 3 months of age
  1. Sameem Tak1,
  2. Mary Barraclough2
  1. 1Department of Paediatrics, Hull and East Yorkshire Hospitals NHS Trust, Hull, UK
  2. 2Department of Paediatrics, Hull and East Yorkshire Hospitals NHS Trust, Hull, UK
  1. Correspondence to Dr Sameem Tak, sameemtak{at}


Partial liquid ventilation using perfluorocarbons is a therapy that was once frequently used in paediatric populations for patients with severe respiratory distress. Perfluorocarbon is a non-toxic, insoluble and radiopaque vector through which improved gas exchange can occur. Two previous cases have been reported of persistent perfluorocarbon residua, identified on imaging years after receiving liquid ventilation therapy. We report a case of perfluorocarbon detection on a CT scan 15 years after liquid ventilation at 3 months of age, and propose the probable mechanism of its appearance. The importance of considering the imaging appearances of ‘pseudo-calcifications’ as a long-term sequela to perfluorocarbon liquid ventilation is emphasised.

  • neonatal and paediatric intensive care
  • paediatrics
  • neonatal intensive care
  • paediatric intensive care
  • mechanical ventilation
View Full Text

Statistics from


  • Contributors Gathering of information, analysis and researching of the report have been done by ST. MB has critically revised and amended the report.

  • Funding This research received no specific grant from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent Parental/guardian consent obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.