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Rare disease
CASE REPORT
Disseminated cryptococcosis in HIV negative patient
  1. Ali Hassoun,
  2. Neha Mehrotra
  1. Department of Infectious Diseases, Alabama Infectious Diseases Center, Huntsville, Alabama, USA
  1. Correspondence to Dr Ali Hassoun, ali_hasoun{at}yahoo.com

Summary

A 52-year-old white diabetic male with 4-weeks history of persistent cough followed by headache, drenching night sweats, low-grade fever, worsening photophobia, nausea and vomiting was presented. Examination was significant for photophobia and diminution of vision. His spinal fluid and blood cultures were positive for Cryptococcus neoformans. Intravenous fluconazole were given for 2 weeks followed by oral fluconazole. There was significant improvement in systemic and ocular symptoms. HIV serology was negative, but his CD4 counts were low with inverted CD4:CD8 ratio.

  • eye
  • meningitis

https://doi.org/10.1136/bcr-2017-223500

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    Footnotes

    • Contributors AH and NM contributed equally to this paper.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Competing interests None declared.

    • Patient consent Obtained.

    • Provenance and peer review Not commissioned; externally peer reviewed.