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Combination drug chemotherapy and massive skeletal allograft in the management of hydatid disease of femur
  1. Deepak Gautam,
  2. Rajesh Malhotra,
  3. Siddharth Dubey
  1. Department of Orthopaedics, All India Institute of Medical Sciences, New Delhi, Delhi, India
  1. Correspondence to Professor Rajesh Malhotra, rmalhotra62{at}


Hydatid disease of long bone is a rare presentation. Chemotherapy and surgery constitute the standard treatment of choice. Non-union of a pathological fracture of femur particularly due to hydatid disease has been known to be resistant to treatment. These resistant cases require combination drug chemotherapy and excision of the lesion. Reconstruction of a large skeletal defect following resection of the lesion poses a challenge to the orthopaedic surgeons. We discuss the staged treatment of hydatid disease of shaft of femur with resection and cement spacer application followed by reconstruction using massive skeletal allograft under cover of combination drug chemotherapy.

  • infections
  • musculoskeletal and joint disorders
  • orthopaedic and trauma surgery
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  • Contributors DG prepared the manuscript. RM is the chief surgeon and provided valuable inputs in drafting the manuscript. SD was responsible for the collection of data and preparation of draft.

  • Funding Wellcome Trust DBT/India Alliance. Grant number: IA/RTF/15/1/1003.

  • Competing interests DG is the recipient of grant from Wellcome Trust DBT/India Alliance.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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