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Invasive papillary breast cancer with Paget’s disease: first reported association and literature review
  1. Geok Hoon Lim1,2,
  2. Jubal Pallavi Chinthala1,
  3. Mihir Ananta Gudi3
  1. 1Breast Department, KK Women’s and Children’s Hospital, Singapore
  2. 2Duke-NUS Medical School, Singapore
  3. 3Department of Pathology, KK Women’s and Children’s Hospital, Singapore
  1. Correspondence to Dr Geok Hoon Lim, ghlimsg{at}


Invasive papillary carcinoma of the breast and Paget’s disease are both rare entities. We report the first known case of invasive papillary carcinoma associated with Paget’s disease in a woman who presented clinically with a nipple mass. While invasive papillary carcinoma has been reported to have an indolent course without need for overtreatment, our patient had unusual unfavourable histological features. Literature review of this rare subtype was performed.

  • breast cancer
  • general surgery

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  • Contributors Conception of study: MAG. Data collection: GHL and JPC. Data analysis: all authors. Manuscript writing: all authors.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.