Article Text

Download PDFPDF
Acute alveolar haemorrhage in hepatitis C-related cryoglobulinaemic vasculitis
  1. Theepika Rajkumar,
  2. Eswari Vilayur
  1. Nephrology and Transplantation Unit, John Hunter Hospital, Newcastle, New South Wales, Australia
  1. Correspondence to Dr Theepika Rajkumar, theepika.rajkumar{at}


We describe a patient with untreated hepatitis C virus (HCV) infection presenting with pulmonary renal syndrome. He rapidly developed bilateral lung infiltrates and respiratory failure, and bronchoscopy confirmed acute alveolar haemorrhage secondary to cryoglobulinaemic vasculitis. Early bronchoscopy to confirm the diagnosis and consequent institution of immunosuppressive therapy led to excellent outcomes, which otherwise is reported in the literature to carry significant mortality. Therefore, in patients with HCV presenting with bilateral lung infiltrates, physicians must maintain a high degree of clinical suspicion for alveolar haemorrhage secondary to cryoglobulinaemic vasculitis.

  • hepatitis C
  • acute renal failure
  • respiratory medicine
  • haematology (incl blood transfusion)
View Full Text

Statistics from


  • Contributors TR: collection of case details and reporting of case and discussion. EV: conception, revision and final approval of the version published.

  • Competing interests None declared.

  • Patient consent Obtained fron next of kin.

  • Provenance and peer review Not commissioned; externally peer reviewed.

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.