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Primary cutaneous osteosarcoma of the scalp
  1. Yusra Al-Janabi1,
  2. Khalid Al-Janabi2,
  3. Kallirroi Tzafetta1,
  4. Mahir Petkar2
  1. 1St Andrews Centre for Plastic Surgery and Burns, Mid Essex Hospital Services NHS Trust, Chelmsford, UK
  2. 2Histopathology Department, Mid Essex Hospital Services NHS Trust, Chelmsford, UK
  1. Correspondence to Dr Yusra Al-Janabi, yusra.alj{at}


Primary cutaneous extraskeletal osteosarcoma (PCEO) is a rare malignant neoplasm with less than 20 cases reported in the literature to date. Presenting as a nodule or mass on the skin, commonly at sites of previous trauma or radiation, these lesions are differentiated from other neoplasms through their characteristic microscopic appearance. This report highlights a case of PCEO in a 75-year-old man with a history of squamous cell carcinoma (SCC) of the scalp. Histological examination of a scalp nodule in the region of a previously excised SCC revealed proliferation of osteoid surrounded by malignant osteocytes. An overview of this condition and differential diagnoses are presented in this report.

  • pathology
  • dermatology
  • plastic and reconstructive surgery
  • head and neck surgery
  • skin cancer
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  • Contributors YAl-J’s role was in the writing of the article, gaining information from patient case notes, reviewing the research. KAl-J’s role was in diagnosis of the case, contribution to case report writing and planning. KT’s role was in patient management, contribution to case writing and planning. MP’s role was his contribution to case writing and planning, obtaining and annotating histology slides.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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