Article Text

Download PDFPDF
CASE REPORT
Granulomatosis with polyangiitis: an unusual cause of acute liver injury
  1. David Owen Rees1,
  2. Anu Gunavardhan2,
  3. David Andrew Glover3
  1. 1Nephrology and Transplant Department, Cardiff and Vale University Health Board, Cardiff, UK
  2. 2Pathology Department, BCU Health Board, Rhyl, UK
  3. 3Nephrology Department, BCU Health Board, Wrexham, UK
  1. Correspondence to Dr David Owen Rees, davidowenrees{at}yahoo.co.uk

Summary

Granulomatosis with polyangiitis (GPA) causing liver injury is rare. Where liver biopsies have been taken findings are not always typical and diagnosis can be challenging. Here, we present a case of a 58-year-old male who on admission to hospital was found to have acute liver injury. Diagnosis of liver involvement in GPA is supported by liver histology and the resolution of hepatitis after commencement of immunosuppressive treatment.

  • renal system
  • immunology
  • acute renal failure
  • hepatitis other

Statistics from Altmetric.com

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Footnotes

  • Contributors DOR conducted literature review and wrote case report. AG interpreted slides and provided images of slides. DAG supervised and edited case report.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.